The aim of this paper is to investigate the physical mechanisms which drive the thermal behaviour of a double-skin photovoltaic (PV) facade, in order to be able to control the energy impact on buildings. The system consists of a channel between the PV collector and the wall of the building that ensures cooling of the PV modules and the recovery of heat to be used in the building. This permits the production of electricity and heating during cold periods (winter) and free cooling (ventilation) during hot periods (summer), whilst at the same time increasing the efficiency of the PV modules by lowering their temperature. Such natural convection systems are difficult to control and require a detailed study to be undertaken. This work focuses on the effects of alternate layering of the PV modules, which induce alternative heating zones, within the double facade. A parametric study has been performed using a RANS code to determine the best spatial configuration to improve the mixing and efficiency of the heat exchange process. The parametric analysis allows us to focus on configurations which will improve flow destabilization and therefore increase the thermal exchanges in the channel.