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ISSN Online: 2377-424X

ISBN Print: 978-1-56700-474-8

ISBN Online: 978-1-56700-473-1

International Heat Transfer Conference 16
August, 10-15, 2018, Beijing, China

NUMERICAL ANALYSIS OF EFFECTIVE DAMAGE RADIUS FOR LARGE TUMOR MICROWAVE HYPERTHERMIA

Get access (open in a dialog) DOI: 10.1615/IHTC16.cms.023389
pages 1769-1776

摘要

Microwave hyperthermia has achieved significant curative results in large tumor (D>2 cm) therapy because of its large ablation area, short treatment time, and the absence of side effects. However, the effective damage radius due to variations in the treat-time and incident power remains highly uncertain. In this study, a simplified two-dimensional axisymmetric mathematic model was established on the basis of single-probe microwave ablation of large liver tumors of radius 2-4 cm. In addition, the optimum damage condition was obtained as 50 °C/13 s by using the standard of the shortest time required for tissue damage at each monitoring point. Ultimately, the maximum damage radius R, the maximum damage depth H, R/H and the effective damage radius Re, were investigated using damaged tissue integral analysis. The results indicate that H increases faster than R over time, and R/H is primarily influenced by the treatment time (up to 0.39-0.42 at 10 min), but was not significantly impacted by the microwave power. More importantly, for a Re of 2 cm, the treatment conditions at different powers were 50-80 W/4 min and 90-150 W/2 min. The required treatment conditions for a Re of 3 cm were 50 W/10 min, 60-80 W/8 min, 90-130/6 min and 140-150 W/4 min. It was also determined that an Re value of 0.04 m was achieved at the maximum power of 150 W for a treat-time of 10 min.